The Division of Investigative Oversight within the U.S. Office of Research Integrity (ORI) is responsible for conducting oversight review of institutional inquiries and investigations of possible research misconduct. It is also responsible for determining whether Public Health Service findings of research misconduct are warranted. Although ORI findings rely primarily on the scope and quality of the institution’s analyses and determinations, ORI often has been able to strengthen the original findings by employing a variety of analytical methods, often computer based. Although (...) ORI does not conduct inquiries or investigations, it has broad authority to provide assistance to institutions at all stages of their reviews of allegations. This assistance can range from providing advice on best practices, to legal assistance, to suggestions for how best to investigate specific allegations. When asked, ORI can also conduct certain forensic analyses, such as a statistical examination of questioned digits or a simple examination of a questioned figure in Photoshop. ORI will not provide opinions or render judgment on such analyses while the institution is still conducting its investigation. Such analyses can be done without knowing much else about the case. (shrink)

Eric T. Poehlman, Ph.D., was an internationally recognized, tenured professor at the University of Vermont (UVM) in Burlington when, in October 2000, a junior member of Poehlman’s laboratory became convinced that he had altered data from a study on aging volunteers from the Burlington area. This suspicion developed into one of the most significant cases of scientific misconduct in the history of the US Department of Health and Human Services’ (HHS) Office of Research Integrity (ORI), launching a US Department of (...) Justice (DOJ) civil and criminal fraud investigation and, eventually, to a much publicized guilty plea and felony conviction. In the end, Dr. Poehlman admitted to 54 findings of scientific misconduct made by the UVM and ORI, agreed to retract or correct ten of his publications and to exclude himself from federal procurement and nonprocurement transactions for life. The United States Government’s handling of this case was distinguished by a highly cooperative approach that integrated the resources of the US Attorney’s Office for the District of Vermont (USAO) and both ORI and the Office of the Inspector General (OIG) in HHS in the common goal of prosecuting research fraud. (shrink)

This book is a volume in the Penn Press Anniversary Collection. To mark its 125th anniversary in 2015, the University of Pennsylvania Press rereleased more than 1,100 titles from Penn Press's distinguished backlist from 1899-1999 that had fallen out of print. Spanning an entire century, the Anniversary Collection offers peer-reviewed scholarship in a wide range of subject areas.

Spanning 1200 years of intellectual history – from the 6th century BCE emergence of philosophical enquiry in the Greek city-state of Miletus, to the 6th century CE closure of the Academy in Athens in 529 – Philosophy of Mind in Antiquity provides an outstanding survey of philosophy of mind of the period. It covers a crucial era for the history of philosophy of mind, examining the enduring and controversial arguments of Plato and Aristotle, in addition to the contribution of the (...) Stoics and other key figures. Following an introduction by John Sisko, fifteen specially commissioned chapters by an international team of contributors discuss key topics, thinkers, and debates, including: the Presocratics, Plato, cognition, Aristotle, intellect, natural science, time, mind, perception, and body, the Stoics, Galen, and Plotinus. Essential reading for students and researchers in philosophy of mind, ancient philosophy, and the history of philosophy, Philosophy of Mind in Antiquity is also a valuable resource for those in related disciplines such as Classics. (shrink)

Japanese pop idols occupy an ambiguous position in the broader popular music landscape, straddling a line between fiction and non-fiction, simultaneously characterological yet physically instantiated. As idealized representations of the girl or boy next door, idols serve as both ‘image characters’ who can be used to sell a variety of products, as well as ‘quasi companions’ meant to provide fans with a manufactured sense of intimacy. Using a joint quantitative and qualitative approach, this article analyses the lyrics of female idol (...) groups. Specifically, I demonstrate how the combination of first- and second-person pronouns and sentence-final expressions are utilized to construct both female-coded and male-coded gendered personae, revealing that idol lyrics engage in the process of cross-gender performance. As a result, through their performance of these personae, female idol groups explicitly reinforce a binary imagination of normative gender expressions, allowing such idol groups to capitalize on idealized heterosexual adolescence through affective resonance and nostalgia. (shrink)

John Stapleford interacts with seven standard introductory economics texts to show how ethics are inextricably intertwined with economic life and analysis. This revised and expanded edition includes discussions of entitlements, global poverty, government debt, healthcare reform and immigration reform.

How well is the field of political studies doing and where is it headed? Such questions are examined and answered in this broad world overview of political science, along with the advances and shortcomings, as well as the recommended prescriptions for the future decades of the new century. The book includes three world regional assessments of the discipline, along with an in-depth survey of various sub-disciplinary fields and a concluding critical essay on the future of political studies. This is the (...) final volume in a book series on the development of political science, created in 2000 by Research Committee 33 of the International Political Science Association (IPSA) on the study of political science as a discipline. Contents include: Political Science in Three Asian Democracies: Disaffected (Japan), Third-Wave (Korea), and Fledgling (China) * Political Science in Europe: Its Development as a Discipline * Political Science in North America and Other Continents: Is There a Genuinely Int. (shrink)

Is morality too difficult for human beings? Kant said that it was, except with God's assistance. Contemporary moral philosophers have usually discussed the question without reference to Christian doctrine, and have either diminished the moral demand, exaggerated human moral capacity, or tried to find a substitute in nature for God's assistance. This book looks at these philosophers--from Kant and Kierkegaard to Swinburne, Russell, and R.M. Hare--and the alternative in Christianity.

This article summarizes a variety of current as well as previous research in support of a new theory of consciousness. Evidence has been steadily accumulating that information about a stimulus complex is distributed to many neuronal populations dispersed throughout the brain and is represented by the departure from randomness of the temporal pattern of neural discharges within these large ensembles. Zero phase lag synchronization occurs between discharges of neurons in different brain regions and is enhanced by presentation of stimuli. This (...) evidence further suggests that spatiotemporal patterns of coherence, which have been identified by spatial principal component analysis, may encode a multidimensional representation of a present or past event. How such distributed information is integrated into a holistic percept constitutes the binding problem. How a percept defined by a spatial distribution of nonrandomness can be subjectively experienced constitutes the problem of consciousness. Explanations based on a discrete connectionistic network cannot be reconciled with the relevant facts. Evidence is presented herein of invariant features of brain electrical activity found to change reversibly with loss and return of consciousness in a study of 176 patients anesthetized during surgical procedures. A review of relevant research areas, as well as the anesthesia data, leads to a postulation that consciousness is a property of quantumlike processes, within a brain field resonating within a core of structures, which may be the neural substrate of consciousness. This core includes regions of the prefrontal cortex, the frontal cortex, the pre- and paracentral cortex, thalamus, limbic system, and basal ganglia. (shrink)

This book, first published in 1990, takes a critical look at the major assumptions which support critical thinking programs and discovers many unresolved questions which threaten their viability. John McPeck argues that some of these assumptions are incoherent or run counter to common sense, while others are unsupported by the available empirical evidence. This title will be of interest to students of the philosophy of education.

The evolution of life on Earth has produced an organism that is beginning to model and understand its own evolution and the possible future evolution of life in the universe. These models and associated evidence show that evolution on Earth has a trajectory. The scale over which living processes are organized cooperatively has increased progressively, as has its evolvability. Recent theoretical advances raise the possibility that this trajectory is itself part of a wider developmental process. According to these theories, the (...) developmental process has been shaped by a yet larger evolutionary dynamic that involves the reproduction of universes. This evolutionary dynamic has tuned the key parameters of the universe to increase the likelihood that life will emerge and produce outcomes that are successful in the larger process (e.g. a key outcome may be to produce life and intelligence that intentionally reproduces the universe and tunes the parameters of ‘offspring’ universes). Theory suggests that when life emerges on a planet, it moves along this trajectory of its own accord. However, at a particular point evolution will continue to advance only if organisms emerge that decide to advance the developmental process intentionally. The organisms must be prepared to make this commitment even though the ultimate nature and destination of the process is uncertain, and may forever remain unknown. Organisms that complete this transition to intentional evolution will drive the further development of life and intelligence in the universe. Humanity’s increasing understanding of the evolution of life in the universe is rapidly bringing it to the threshold of this major evolutionary transition. (shrink)

As a work of a scholarship it seems to me to compare favourably with the best books on the subject, including those by Marcus Singer and Onora Nell.' Prof.

In these previously uncollected essays, Smith argues that American philosophers like Peirce, James, Royce, and Dewey have forged a unique philosophical tradition—one that is rich and complex enough to represent a genuine alternative to the analytic, phenomenological, and hermeneutical traditions which have originated in Britain or Europe. "In my judgment, John Smith has no equal today in combining two scholarly qualities: the analysis of philosophical texts with penetration and rigor, and the discernment of what it is in these texts (...) that matters. These qualities are in evidence throughout the essays in _America's Philosophical Vision._ Whether he is evaluating Rorty's view of Dewey; the pragmatic theory of experience and truth; theories of freedom, creativity, and the self; Royce's conception of community; or synoptic philosophic visions, Smith always succeeds in uniting a comprehensive understanding of philosophic writings with a sure grasp of their import for human culture and aspiration. It is a great benefit to students of American thought that these papers have now been collected into one volume."—James Gouinlock, Emory University. (shrink)

This research examines the concept of entrepreneurial learning and relates it to Deepak Chopra's seven spiritual laws of success. The article first examines generic processes in motivating entrepreneurs to engage in self-directed learning projects on behalf of their businesses. Then it examines three modes of learning as they apply to practising entrepreneurs. Triple-loop learning is proposed as the deepest level of entrepreneurial learning. Triple-loop learners are considered the most likely entrepreneurs to practise the seven spiritual laws of success. Finally, each (...) of the seven laws is related back to the motives that inspire entrepreneurs to learn. (shrink)

Introduction Marxism is a set of ideas from which sprang particular approaches to economics, sociology, anthropology, political theory, literature, art, ...

_A new theory of how and why we cooperate, drawing from economics, political theory, and philosophy to challenge the conventional wisdom of game theory_ Game theory explains competitive behavior by working from the premise that people are self-interested. People don’t just compete, however; they also cooperate. John Roemer argues that attempts by orthodox game theorists to account for cooperation leave much to be desired. Unlike competing players, cooperating players take those actions that they would like others to take—which Roemer (...) calls “Kantian optimization.” Through rigorous reasoning and modeling, Roemer demonstrates a simpler theory of cooperative behavior than the standard model provides. (shrink)

Despite the frivolous note implied in the popular expression, ‘The Greeks had a word for it’, the literal truth is that they did! Time and again we find reflected in the terminology developed by these ancient seekers after wisdom, an attention to important distinctions and a faithfulness to the details of actual experience which are truly remarkable. The Greek thinkers had, as every classical scholar and student of Greek philosophy knows, a finely developed philosophical language, one sensitive no less to (...) the unusual, pregnant experience than to the familiar details of ordinary life. (shrink)

This work is an exploration of divine command theory, which is the theory that what makes something morally obligatory is that God commands it.

If one is an egalitarian, what should one want to equalize? Opportunities or outcomes? Resources or welfare? These positions are usually conceived to be very different. I argue in this paper that the distinction is misconceived: the only coherent conception of resource equality implies welfare equality, in an appropriately abstract description of the problem. In this section, I motivate the program which the rest of the paper carries out.

The recent challenge of Dynamical Systems Theory to the social sciences, is based largely on the beliefthat processes in the social arena can be considered as analogous to those of the natural world, and that in consequence general theoretical advances in explaining the latter might with advantage be applied to the former. This paper aims to show that claims for Dynamical Systems Theory with respect to the understanding or measurement of social processes would be premature; the reasons for this lying (...) not only in the unfamiliarity and operational difficulties of Dynamical Systems Theory in itself, but also in the problematic nature and history of our usage of the term ‘social process’. Reviewing some examples of such usage from Sociology and Social Psychology, it is concluded that Dynamical Systems Theory might serve as a catalyst for a re-examination of existing orthodoxies and major concepts, but that progress would be retarded by the uncritical application of it's terminology, concepts, and techniques of mathematical modelling, without this prior and demanding first step. (shrink)

We prove the following extension of a result of Keisler and Morley. Suppose U is a countable model of ZFC and c is an uncountable regular cardinal in U. Then there exists an elementary extension of U which fixes all ordinals below c, enlarges c, and either (i) contains or (ii) does not contain a least new ordinal. Related results are discussed.

In his Target Article, Terrence Deacon develops simple models that assist in understanding the role of RNA in the origins of life. However, his models fail to adequately represent an important evolutionary dynamic. Central to this dynamic is the selection that impinges on RNA molecules in the context of their association with proto-metabolisms. This selection shapes the role of RNA in the emergence of life. When this evolutionary dynamic is appropriately taken into account, it predicts a role for RNA that (...) is consistent with the Managed-Metabolism Hypothesis about the origins of life, and inconsistent with Deacon’s account. (shrink)

Referring to some perceived difficulties in social representation theory, this paper offers an account of the genesis of social representations in a theory of valuing. Drawing on influential but previously largely unconnected ideas from interactionist theory, personal construct theory, and Rokeach’s theory of values, it is suggested that a process of valuing can be presented as a crucial link between the individual and social levels of analysis, a present theoretical disjuncture that has been of concern to some commentators in social (...) representations and widespread beliefs. (shrink)

Anthromes, or anthropogenic biomes, characterize the globally significant ecological patterns shaped by sustained direct human interactions with ecosystems, including agriculture, urbanization, and other land uses. The emergence of anthromes has literally paved the way for the Anthropocene, and now cover more than three quarters of Earth’s ice-free land surface, including dense settlements, villages, croplands, rangelands, and cultured lands; wildlands untransformed by agriculture and settlements cover the remaining area.

Is inheritable genetic modification the new dividing line in gene therapy? The editors of this searching investigation, representing clinical medicine, public health and biomedical ethics, have established a distinguished team of scientists and scholars to address the issues from the perspectives of biological and social science, law and ethics, including an intriguing Foreword from Peter Singer. Their purpose is to consider how society might deal with the ethical concerns raised by inheritable genetic modification, and to re-examine prevailing views about whether (...) these procedures will ever be ethically and socially justifiable. The book also provides background to define the field, and discusses the biological and technological potential for inheritable genetic modification, its limitations, and its connection with gene therapy, cloning, and other reproductive interventions. For scientists, bioethicists, clinicians, counsellors and public commentators, this is an essential contribution to one of the critical debates in current genetics. (shrink)

The popular belief that religion is the same everywhere or that all religions are ‘at bottom’ identical in essentials is a widespread falsehood that is saved from being completely worthless by the fact that religion does exhibit a universal or common structure wherever it appears. This structure is intimately related to the structure of human life in the world. The enduring pattern that enables us to understand religions widely separated in both time and space depends largely on the fact that (...) man and the process of human life in the world have their own structures which remain, despite the undeniable variety introduced by vast differences of culture, ethnic features, geographical location, climate etc. Structure means pattern or form; it is reality significantly organised. It can be grasped as that which endures above and beyond changing historical details. Because human life has a structure, we are able to understand the wrath of Achilles or sympathise with the love of Abélard for Héloïse although we are separated from both by centuries of time. (shrink)

Utilitarians, maximinners, prioritarians, and sufficientarians each provide examples of situations demonstrating, often apparently compellingly, that a sensible ethical observer must adopt their view and reject the others. I argue, to the contrary, that an attractive ethic is eclectic or pluralistic, in the sense of coinciding with these apparently different views in different regions of the space of social states. I reject the view that an appealing ethic can be universally maximin, prioritarian, or utilitarian. Key Words: distributive justice • utilitarianism • (...) maximin • sufficiency • priority. (shrink)

Examines Arthur Schopenhauer's (1788-1860) conception of human agency and responsibility, his unique ethics of the morally virtuous character, and his assessment of life as fundamentally suffering. This title focuses on his contention that the human will and the human body cannot have a cause and effect relationship with each other.